Leg Cramp Relief Product Buyer’s Guide (updated May 2024)

Cramprin Review



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Our research has shown that this manufacturer has created a product born from science and clinical data. We found that this was the only product to contain the exact vitamins, minerals and herbs which have been clinically proven to reduce and prevent painful leg cramp symptoms and muscle spasms as well as to soothe sore muscles and stimulate muscle relaxation. Moreover, it includes BioPerine® for enhanced bioavailability and faster results. Dosage is based on clinical studies which suggest that these guys are serious about what they do. We liked that it’s served in a vegan-friendly capsule as well as offers a 60-day money-back guarantee if you are not happy with the results. What have you got to lose? Nothing! Except for the leg cramps!

Why do we recommend Cramprin?

Main Benefits:

  • It contains high-absorbing, non-laxative Magnesium Glycinate which is crucial for maintaining normal muscle and nerve function. 
  • It contains B-Sci™, a unique, patented vitamin B complex containing vitamins B1, B2, B3, B5, B6, B9, B12 and Biotin, which are clinically proven to reduce the frequency, intensity and duration of leg cramps. 
  • It contains Chamomile to increase glycine levels to relax muscles and relieve painful spasms. 
  • It contains Ginger to stimulate blood circulation for fast relief from involuntary muscle spasms. 
  • It contains BioPerine® which is a patented form of Piperine that has been proven to increase bioavailability, for a more effective product.
  • It does not contain any preservatives, artificial colorings, hormones, or unnecessary ingredients that may dilute the efficacy of the product.
  • We found so many supportive consumer reviews from users who had experienced excellent results, some within as little as a week.
  • Its daily suggested serving is the optimal potency as recommended by doctors for effectiveness and is supported by extensive clinical research trials and studies.
  • This manufacturer’s customer service is second to none, it provides excellent support and help. Furthermore, it offers an excellent money-back guarantee if customers are not happy with their results.

This unique formula was the only one that we could find that was backed by solid clinical data and included this specific blend of ingredients in their potent doses.   


When you experience the extreme pain of leg cramps, it can literally bring you to your knees. Tight, clenched muscles can strike at any moment, whether you’re in the middle of your day or in the middle of your sleep and leave you with tired, sore muscles. Dietary changes may help but will not bring you immediate relief. Alongside dietary and lifestyle changes, there are many ingredients that have been linked to help target the root cause of leg cramps for natural relief from painful symptoms as well as to naturally induce muscle relaxation. There are several key studies that help pinpoint the way when it comes to finding the most effective oral supplement to address and prevent muscles from seizing up as well as to help overtrained muscles relax and recover.   

First and foremost, leg cramp supplements must be made using pure and natural ingredients so that they are safe for long-term use to address the root cause of muscle spasms. Using anything less will compromise the quality of the product you receive.

Secondly, the inclusion of Magnesium as Magnesium Glycinate is crucial for maximum absorption into the small intestines. Magnesium is a mineral that has been shown to help maintain optimal nerve and muscle function, however, it comes in many different forms as Magnesium chemically binds to different compounds, some of which have extreme difficulty absorbing into the body. Magnesium Glycinate, therefore, is a high-absorbing type that is more bioavailable which ensures it absorbs easily into the body, leaving hardly any behind so that there is no laxative effect. A quality formula must contain at least 400 mg of Magnesium Glycinate.

Thirdly, there have been successful studies over many years, around the globe confirming that B vitamins alleviate the frequency, intensity and duration of leg cramp pain. This formula contains B-Sci™, a patented and trademarked vitamin B complex containing vitamin B1 (as Thiamine HCI), vitamin B2 (as Riboflavin), vitamin B3 (as Niacin), vitamin B5 (as Calcium Pantothenate), vitamin B6 (as Pyridoxine), Biotin, Folate (as Folic Acid) and vitamin B12 (as Cyanocobalamin).

Fourthly, Chamomile must be part of a muscle-relieving supplement and, unfortunately, many brands don’t include this. Chamomile increases glycine, which is an amino acid that promotes muscle relaxation.

Fifthly, Ginger is essential for relieving muscle spasms as it is proven in clinical studies to stimulate circulation in the body. Many formulas mistakenly leave this out.

Finally, the inclusion of BioPerine® ensures maximum uptake of ingredients by the body leading to speedy results for swift relief from painful symptoms of leg cramps.  

Many companies who enjoy a positive reputation, take advantage of their good standing with the public in order to sell cheap health supplements. It’s so distressing how easy it is, which is why it is incumbent on every consumer to do their own fact-finding on any health product they purchase.

Cramprin contains effective ingredients to address the root cause of leg cramps as well as to promote healthy sleep. What we really like is that it is made by a company that consistently uses clinical studies as a benchmark for the dosage of all their health supplements. There is also a money-back guarantee which can be claimed by speaking to their customer service agents who are real, not just bots!

Additionally, you will not find any ingredients in Cramprin which shouldn’t be there. There are no added fillers, binders, additives or preservatives. There are so many products out there that do not fall within the realm of high standards, offering artificial alternatives and all sorts of extras inside their formulas. It is a relief to be able to recommend a company that manufactures such a unique, well-researched product.

To summarize, Cramprin uses top-quality natural ingredients, provides awesome results, has a caring customer support team and a great price. From what we saw, without a doubt, this is an extremely good product.

Quality Assurance

Over the last few years, we understand how consumers have grown skeptical of nutritional health supplements. This simply comes down to shady companies providing useless formulas that contain unrelated and useless ingredients or that add fillers or binders to their products. Often, these ingredients are not pure, or have not been tested for quality and have no scientific validity as to why they have been included in the formulas. Not only is this irresponsible, but often quite dangerous. Truth being, there is absolutely no reason why anything artificial should be added. Natural and pure is the best.

On many nutritional supplements, the label states that the ingredients are either ‘active’ or inactive’. In simple terms, the active ingredients are the reason you decided to purchase the product and the ones that actually bring you the results you are hoping for. When you see a long list of inactive ingredients, beware, often companies will fill their products with unhelpful and potentially dangerous junk.

That is why, for us, Cramprin is a product that does not fall within this category. Its formula contains only natural and pure ingredients backed by numerous clinical studies and research. It offers a simple philosophy that seems to work well – offer top-quality ingredients in the most effective potency, great price options with a terrific money-back guarantee and you won’t be disappointed.

Another aspect of taking supplements that contain a large amount of inactive or unnecessary ingredients is the lack of understanding of how these chemicals may affect existing medical conditions or medications. If the ingredients are bona fide and in their natural form, side effects or negative interactions are unlikely to be experienced.

We were very happy to discover that Cramprin is manufactured in an FDA-registered facility. What’s more, is that it is cGMP recognized and complies with the US Pharmacopeia’s standards for quality and purity. This suggests that this company takes what it does very seriously, and strives to keep its products safe, natural and effective – a mentality that we totally appreciate.


Cramprin by Approved Science comes at an affordable price with some excellent multiple purchase deals, allowing for huge cost savings for consumers. Also, this company is staunchly against any auto-ship programs, as they can be nearly impossible to cancel.

Nowadays, consumers need to be ‘smart shoppers’, carrying out as much research as they can about what they would like to purchase, in order to avoid wasting their money. There are many options out there that charge a lot of money for inferior products that simply will not deliver the results that they promise. This is disheartening and quite frankly, a bad and dishonest practice.

Orders are shipped within 24 hours, with the exclusion of any orders placed on weekends and holidays. They are wrapped and sent in discreet packaging, with no identifying marks on the outside, unlike other companies that often have embarrassing slogans or logos. Furthermore, this company provides a 60-day risk-free money-back guarantee. If you are not 100% happy with the results, you are able to return the product and receive a full refund. That shows strong confidence in its product and we totally support that kind of guarantee.

In Conclusion

When people are searching for a good product to eliminate painful leg cramps and muscle spasms, they focus on short-term relief from topical creams instead of attacking the root of the problem. Leg cramps are due to a conglomerate of issues including contracted muscles, constricted blood vessels and low levels of B vitamins and Magnesium.

Cramprin specifically contains the optimal blend of ingredients that are clinically proven to put an end to the uncomfortable and painful symptoms of leg cramps to allow you to continue with your day or continue sleeping throughout the night. They are:

  • High-absorbing Magnesium Glycinate for optimal muscle and nerve function.
  • B-Sci™, a patented vitamin B complex for reducing the frequency, intensity and duration of natural leg cramps.
  • Chamomile to increase glycine levels to relax muscles and relieve painful spasms. 
  • Ginger to stimulate circulation for muscle-spasm relief. 
  • BioPerine®  proven to increase bioavailability for speedy relief.

Additionally, there are other significant elements to bear in mind, such as third-party testing and comprehensive customer reviews that give us a great indication of how the product really works.

Of all the products that we reviewed, across all parameters, none compared to Cramprin. If you are looking for a top-quality formula backed by research and scientific data that is an effective, long-term solution to relieving painful symptoms of leg cramps by stimulating circulation and enhancing muscle relaxation as well as preventing them from returning with a vitamin and mineral-rich formula, you would be hard pushed to find anything better than Cramprin.

Approved Science Cramprin
Elym & Rye Magnesium
Crystal Star Muscle Relax
LA Synergy Quina
Contains High-Absorption Magnesium Glycinate for Optimal Muscle Function
Contains B-Sci™, a Patented vitamin B Complex to Promote Blood Flow
Contains Chamomile to Relax Muscles
Includes Ginger to Stimulate Circulation to Alleviate Muscle Spasms
Includes BioPerine® (Piperine) for Faster Results
Third-party tested for purity
No additives, preservatives, or artificial ingredients
Money-Back Guarantee

Read on to see what their happy customers are saying

“I used to have excruciating leg cramps from my thigh to my feet.  The worst part is that they would come out of nowhere. I could be sitting in my dentists’ waiting room or lying in bed at night and my legs would suddenly spasm and seize up. It was so painful. However, after taking Cramprin my leg cramps have 90% diminished. At this point, I might get a cramp in my calf once in a while and then I’ll realize I forgot to take a tablet. With Cramprin I don’t have any side effects. The dose works for me and keeps me feeling good all day. I used to have to work in rest periods during the day because my muscles were so sore but now I can get so much more done! I’ll be so glad if my review helps someone as much as this product helps me!”  – Vicky Robins

“I tried Cramprin out of desperation. My friend gave me 2 of her pills to try because she knows how I can’t sleep due to my horrible leg cramps. It was the first time I slept well in 15 years! Some nights I woke up crying from the pain. I had gotten so bad that I can’t even walk after a cramp passes because my legs get so tired and strained. I tried other magnesium supplements, on the advice of my doctor, but none of them worked. I’ve also tried every leg cramp product but many of them only work once you have a cramp, so I was still woken up at night. At one point I was prescribed muscle relaxers but I couldn’t take the side effects. I’m so glad my friend persuaded me to try Cramprin. Last night was heaven! It felt wonderful. The first thing I did this morning was order a supply for myself. These pills pack a punch for getting rid of leg cramps. I am very satisfied.  It’s also a win-win situation because Approved Science has a 100% money back policy on returns. You literally can’t loose.” – Emily Hall   


“My cramps were severe. Not only in my legs but also in my stomach and back. In general, I have a high tolerance for pain, but these cramps could reduce me to tears. My physician offered me drugs but I prefer to find alternate ways of healing my body instead of just turning to drugs as a default option. After reading reviews and trying different natural treatments, I found Cramprin and as they say, the rest is history. This is the perfect solution for me. I will never be without Cramprin again! I don’t know who developed this wonderful pill but I am so thankful they did!” – Colin Garrison       


“I am chronically deficient in Magnesium, so I’m always trying different types of Magnesium in order to find the best absorption levels for my body. Based on articles I’ve read, I thought I would give this brand a try. I started taking Cramprin a week ago and the big difference is that I don’t feel cramps coming on. It used to be that I would be able to take something when I felt cramps were about to start but now there’s nothing! I will update after I’ve used Cramprin for about a month. Update: this is definitely working. I find that taking one pill keeps the cramps away and this way I’m able to stretch one bottle over 2 months. This is excellent!”  – Dan Braxton

“Cramprin does what it says it will do. I suffered a knee injury that was taking forever to heal, plus I have bursitis in my hip joints that was so painful, I could hardly walk. I relied on prescription meds to handle the pain but they made me so sleepy that I was going through my day in a fog. I started taking Cramprin and felt relief from the first day. There is no drowsiness or laxative effect that some other cramp relief products have. My knee injury has finally started to heal and my bursitis is a lot more manageable. Since using Cramprin I have ordered other Approved Science products and they have also worked really well. I will be using Cramprin for a long time and I am grateful to have found it. Highly recommended.” – Mimi Sinclair

“After a workout, my muscles cramp up like crazy. I stretch, do yoga, don’t overtrain and still, nothing I would do could prevent the cramping attacks. For a while, I just suffered through it. I refuse to give up my daily exercise but the constant cramps were starting to wear on me. I read everything I could about post-workout muscle recovery and tried various products. In the end, Cramprin worked best. It’s a huge relief to feel like myself again.” – Tyler Burns         

“I’ve suffered from leg cramps and Fibromyalgia for many years so I am thrilled that this product really works! The first time I tried Cramprin was at night and within half an hour, I was so calm and pain free that I could fall asleep. I never left a product review for anything before but I couldn’t help myself this time! I’ve been taking one tablet at the beginning of the day and one in the evening and I’ve been free of cramps all day long. The customer service department at Approved Science has been so accessible and informative, which is not a given. Overall, this has been such a positive experience for me. I hope Cramprin can help others too.” – Bella Pearce

FAQs about Cramprin:

How does Cramprin by Approved Science work?

The key lies in the ingredients contained within this formula – they haven’t simply been plucked from thin air so that they have a list of ingredients that looks good on the label! Each ingredient in this product is supported by clinical research and has a reason to be there! Its unique formula is based on clinical studies that have shown huge promise to relieve painful leg cramps as well as to prevent muscle spasms from returning. By including key ingredients to target vitamin and mineral deficiencies associated with leg cramps, it works to promote muscle and nerve function, boost leg circulation, enhance muscle relaxation and soothe sore muscles. It has included effective ingredients including Magnesium, B vitamins and herbs in a highly effective dose to ensure optimal effects and fast results of the effective approach to relieve agonizing legs cramps at their source.

What’s more, this product includes BioPerine® for enhanced absorption and faster results. This unique formula works to relieve the tight, painful contractions of muscle cramps and ensure they don’t not come back. The great thing is that this formula is all-natural which means that it is safe for long-term use.

Do all Leg Cramp Relief products work in a similar way?

The short answer is basically no, they do not. There are many companies that just ride the trends, producing inferior products with weak formulas in the wrong proportions. Many use incorrect ingredients, fillers, binders or even worse ingredients that can affect desired results, and even be dangerous.

What should I look for in an effective Leg Cramp Relief formula?

  • It should contain Magnesium Glycinate for high absorption into the intestinal walls. 
  • It should contain a Vitamin B complex to reduce the frequency, intensity, and duration of nocturnal leg cramps.
  • It should contain Chamomile to increase glycine which relaxes muscles.
  • It should contain Ginger which is clinically proven to relieve muscle spasms.
  • It should contain BioPerine® proven to increase bioavailability for speedy relief.
  • It should not contain any binders, fillers, additives, hormones, preservatives or artificial ingredients.
  • It must be 100% pure, natural and with no unnecessary ingredients that could reduce the effectiveness of the product.
  • It should be formulated using the same potency as found effective in clinical studies.

Are there any side effects noted when using this product?

Our research did not uncover any negative side effects when using this product. The ingredients that are contained within the formula of Cramprin are all natural and pure, what’s more, they are doctor approved, so the lack of any negative effects is to be expected. That said, as with any supplement, we always recommend consulting with a doctor if you are pregnant, breastfeeding, have an existing medical condition or are taking any other medication.

What are the dosage instructions for Cramprin?

The manufacturers of this product suggest taking 2 capsules per day, preferably before mealtime with a glass of water. 

As with any medication or supplement, always follow the recommended dosage instructions and do not exceed them as this poses health risks.

How long before I can see any results?

Results will vary for each person. For some, they will see changes almost immediately, for others it may take longer. It is different for each person. Other factors that affect results can include age, diet, and lifestyle so it is hard to say exactly. What you should look out for are those companies that offer a satisfaction guarantee. This suggests that they are confident that their products will deliver the desired results. And after all, if you don’t get the results you were hoping for you can always return the product. Cramprin offers a great money-back guarantee and awesome feedback on how well this product works.

What price should I expect to pay?

The costs of products vary among manufacturers. Unfortunately, many are cheap, useless supplements that have been formulated without any science-based evidence to back them up. Some of these companies are selling their products for over $100 per bottle, which is very expensive. On average, the best supplements we found are selling between the $40-$50 price range. Often, when products appear cheaper, this is indicative of low quality or a low recommended daily serving, which will not bring the results you are looking for. Be aware. Read the labels.

Which Leg Cramp Relief product should I buy?

As each person’s experience of a product is different, it is difficult to say specifically which one is the best. That said, based on several factors, we did like Cramprin. We found that from 50+ products that we looked at, Cramprin had the best quality of ingredients, potency and strength, positive consumer feedback and the manufacturer’s customer service was excellent.

How safe is it to order over the internet?

Cramprin is safe to be ordered over the internet. The manufacturer utilizes the latest encryption software to protect your credit card information and do not engage in shady schemes such as ‘automatic billing’ programs like many other companies do. They also deliver very efficiently and quickly, using discreet packaging.

Why should I choose Cramprin?

There are several reasons why we liked this product including purity of ingredients, customer service, satisfaction, and effectiveness. Its formula is backed by clinical studies and we feel it values consumers’ health above and beyond the profit margins.

This is a great product that you can depend on. It has a well-researched formula with the right ingredients in the correct potency. And if that wasn’t enough, check out the customer reviews – they say it all. It counts with many happy customers clearly singing the praises of this trustworthy product who are highly loyal to this brand. We will summarize the key benefits one more time:

  • It contains high-absorbing, non-laxative Magnesium Glycinate which is crucial for maintaining normal muscle and nerve function. 
  • It contains B-Sci™, a unique, patented vitamin B complex containing vitamins B1, B2, B3, B5, B6, B9, B12 and Biotin, which are clinically proven to reduce the frequency, intensity and duration of leg cramps. 
  • It contains Chamomile to increase glycine levels to relax muscles and relieve painful spasms. 
  • It contains Ginger to stimulate blood circulation for fast relief from involuntary muscle spasms. 
  • It contains BioPerine®  proven to increase bioavailability for speedy relief.
  • It does not contain any binders, fillers, additives, hormones, preservatives or artificial ingredients.
  • Its formula does not contain any synthetic additives, hormones, preservatives, binders, fillers or other unnecessary ingredients.
  • Its lab is FDA and cGMP recognized.
  • Its products comply with the standards for quality and purity outlined by the U.S. Pharmacopeia
  • This product is well priced and falls below average when compared to other similar products. The manufacturer of Cramprin also provides some great discounts for multiple purchases, which can save consumers a lot of money.
  • Our research showed that the company is trustworthy, reliable, transparent and has integrity and a great reputation in the industry.
  • The manufacturer of Cramprin offers a great 60-day money-back guarantee which can be utilized, no questions asked if you are not happy with the results. This shows that the manufacturer has a strong confidence in its products.

The Bottom Line

At the end of the day, the bottom line is that consumers have so many options when choosing a health supplement. We are constantly being bombarded with commercials, advertisements and messages about so many different products, for varying health issues that it is beyond confusing which ones are the real deal and which ones are a waste of time. Leg cramp relief supplements are no exception, with many companies simply trying to cash in on the latest health trends and pushing their products on unwilling consumers.

We like Cramprin because we feel that this company is different. It is in it for the long haul. It has researched its ingredients well and produced its formula using only pure natural ingredients with a lot of clinical data to back them up. The manufacturer of Cramprin offers what more companies should – an effective, affordable product supported by a real concern for the health of their customers. As an added bonus, Cramprin has many happy testimonials to support our belief that this is a great product and a great company.   

What You’ll Discover:

Which Leg Cramp Product is the BEST BUY and comes with a great GUARANTEE!
Which formula and ingredients are the most EFFECTIVE and work the fastest?
How NOT to get ripped off! BE AWARE of poor quality and cheap products.

Top 6 Items to Consider:

  1. Ingredients
  2. Cost Per Serving
  3. Product’s Testing Results
  4. Company’s Reputation
  5. Consumer Reviews
  6. Return Policy & Satisfaction Guarantee

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